Gene

Shal

Species
Drosophila melanogaster
Symbol
Shal
Name
Shaker cognate l
Synonyms
  • CG9262
  • DNK[[v]]4
Biotype
protein coding gene
Automated Description
Enables A-type (transient outward) potassium channel activity. Involved in associative learning and chemical synaptic transmission. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated potassium channel complex. Predicted to be active in membrane. Is expressed in several structures, including adult head; embryonic hindgut; ganglia; larval muscle system; and larval visceral muscle cell. Human ortholog(s) of this gene implicated in Brugada syndrome 9 and spinocerebellar ataxia type 19/22. Orthologous to several human genes including KCND3 (potassium voltage-gated channel subfamily D member 3).
FB Description
Shaker cognate l (Shal) encodes a voltage-dependent A-type K[+] channel. It contributes to neuronal excitability, regulating synaptic plasticity, locomotion, learning, and lifespan.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11537
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
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19.568M19.570M19.572M19.574M19.576M19.578M19.580M19.582M19.584M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions