Gene

mt:ND2

Species
Drosophila melanogaster
Symbol
mt:ND2
Name
mitochondrial NADH-ubiquinone oxidoreductase chain 2
Synonyms
  • CG34063
  • dND2
Biotype
protein coding gene
Automated Description
Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in mitochondrial electron transport, NADH to ubiquinone. Part of respiratory chain complex I. Is expressed in adult head. Used to study mitochondrial metabolism disease. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; multiple sclerosis; myocardial infarction; neurodegenerative disease (multiple); and urinary bladder cancer. Orthologous to human MT-ND2 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2).
FB Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR46552
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
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Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions