Gene

vkg

Species
Drosophila melanogaster
Symbol
vkg
Name
viking
Synonyms
  • 1209
  • 6072
Biotype
protein coding gene
Automated Description
Predicted to be an extracellular matrix structural constituent conferring tensile strength. Involved in Malpighian tubule development; basement membrane organization; and somatic muscle development. Located in basement membrane. Is expressed in several structures, including adult CNS glial cell; circulatory system primordium; embryonic/larval hemocyte; fat body; and gut section. Human ortholog(s) of this gene implicated in brain small vessel disease 1; myocardial infarction; retinal arterial tortuosity; and uterine fibroid. Orthologous to human COL4A1 (collagen type IV alpha 1 chain).
FB Description
viking (vkg) encodes a subunit of Collagen IV and a major component of basement membranes. It is secreted by haemocytes and fat body cells and is required for the normal morphogenesis of many tissues. It also contributes to TGF-beta signalling in the early embryo and the developing Malpighian tubules.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24023
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
5.014M5.016M5.018M5.020M5.022M5.024M5.026M5.028M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions