Gene

wnd

Species
Drosophila melanogaster
Symbol
wnd
Name
wallenda
Synonyms
  • CG8789
  • DLK
Biotype
protein coding gene
Automated Description
Predicted to enable protein kinase activity. Involved in several processes, including collateral sprouting of injured axon; memory; and regulation of synapse organization. Located in axon and neuromuscular junction. Is expressed in several structures, including adult mushroom body; antennal anlage; antennal primordium; brain; and head epidermis primordium. Orthologous to human MAP3K12 (mitogen-activated protein kinase kinase kinase 12) and MAP3K13 (mitogen-activated protein kinase kinase kinase 13).
FB Description
wallenda (wnd) encodes a kinase in the mixed lineage family of MAP Kinase Kinase Kinases. Its roles include axonal injury signaling (it becomes activated in neurons after axotomy), and in regulation of the structure of presynaptic boutons.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23257
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
19.626M19.628M19.630M19.632M19.634M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions