Predicted to enable protein kinase activity. Involved in several processes, including collateral sprouting of injured axon; memory; and regulation of synapse organization. Located in axon and neuromuscular junction. Is expressed in several structures, including adult mushroom body; antennal anlage; antennal primordium; brain; and head epidermis primordium. Orthologous to human MAP3K12 (mitogen-activated protein kinase kinase kinase 12) and MAP3K13 (mitogen-activated protein kinase kinase kinase 13).
FB Description
wallenda (wnd) encodes a kinase in the mixed lineage family of MAP Kinase Kinase Kinases. Its roles include axonal injury signaling (it becomes activated in neurons after axotomy), and in regulation of the structure of presynaptic boutons.