Gene

HP1c

Species
Drosophila melanogaster
Symbol
HP1c
Name
Heterochromatin Protein 1c
Synonyms
  • CG6990
  • Heterochromatin protein 1c
Biotype
protein coding gene
Automated Description
Enables chromatin binding activity; histone reader activity; and methylated histone binding activity. Involved in regulation of transcription by RNA polymerase II and subtelomeric heterochromatin formation. Located in euchromatin; nucleus; and polytene chromosome interband. Part of protein-containing complex. Is expressed in several structures, including adult head; central brain primordium; ganglia; gonad; and larval nervous system. Orthologous to human CBX1 (chromobox 1) and CBX5 (chromobox 5).
FB Description
Heterochromatin Protein 1c (HP1c) encodes a chromatin binding protein that is involved in telomere capping and transcription regulation and interacts with the zinc-finger proteins encoded by woc and row.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22812
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
22.7457M22.7458M22.7459M22.7460M22.7461M22.7462M22.7463M22.7464M22.7465M22.7466M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions