Gene

Socs36E

Species
Drosophila melanogaster
Symbol
Socs36E
Name
Suppressor of cytokine signaling at 36E
Synonyms
  • anon-EST:Liang-2.2
  • CG15154
Biotype
protein coding gene
Automated Description
Enables cytokine receptor binding activity and sevenless binding activity. Involved in several processes, including border follicle cell migration; negative regulation of signal transduction; and wing disc morphogenesis. Is expressed in several structures, including cardiogenic mesoderm; clypeo-labral primordium; follicle cell; gut section; and muscle cell. Orthologous to several human genes including SOCS4 (suppressor of cytokine signaling 4).
FB Description
Suppressor of cytokine signaling at 36E (Socs36E) encodes a negative regulator of the JAK/STAT and EGFR pathways. It is a transcriptional target of the product of Stat92E that mediates lysosomal degradation following pathway stimulation and inhibits basal pathway activity.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10155
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R6
Viewer Help
18.140M18.142M18.144M18.146M18.148M18.150M18.152M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions