Enables cytokine receptor binding activity and sevenless binding activity. Involved in several processes, including border follicle cell migration; negative regulation of signal transduction; and wing disc morphogenesis. Is expressed in several structures, including cardiogenic mesoderm; clypeo-labral primordium; follicle cell; gut section; and muscle cell. Orthologous to several human genes including SOCS4 (suppressor of cytokine signaling 4).
FB Description
Suppressor of cytokine signaling at 36E (Socs36E) encodes a negative regulator of the JAK/STAT and EGFR pathways. It is a transcriptional target of the product of Stat92E that mediates lysosomal degradation following pathway stimulation and inhibits basal pathway activity.