Gene

Smyd3

Species
Rattus norvegicus
Symbol
Smyd3
Name
SET and MYND domain containing 3
Synonyms
  • histone-lysine N-methyltransferase SMYD3
  • LOC498295
Biotype
protein coding gene
Automated Description
Predicted to enable RNA polymerase II complex binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and histone methyltransferase activity. Predicted to be involved in methylation. Predicted to act upstream of or within several processes, including cellular response to dexamethasone stimulus; nucleosome assembly; and regulation of protein phosphorylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus. Orthologous to human SMYD3 (SET and MYND domain containing 3).
RGD Description
Predicted to enable RNA polymerase II complex binding activity; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and histone methyltransferase activity. Predicted to act upstream of or within several processes, including cellular response to dexamethasone stimulus; nucleosome assembly; and regulation of protein phosphorylation. Predicted to be located in cytosol and nucleoplasm. Orthologous to human SMYD3 (SET and MYND domain containing 3); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12197
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

No paralogs for the gene.

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
mRatBN7.2
Viewer Help
90.75M90.80M90.85M90.90M90.95M91.00M91.05M91.10M91.15M91.20M91.25M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions