Gene

CSC1

Species
Saccharomyces cerevisiae
Symbol
CSC1
Name
Calcium permeable Stress-gated cation Channel
Synonyms
  • YLR241W
Biotype
protein coding gene
Automated Description
Enables calcium-activated cation channel activity. Involved in monoatomic cation transport. Located in endoplasmic reticulum and fungal-type vacuole membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 87 and hypomyelinating leukodystrophy 19. Orthologous to several human genes including TMEM63A (transmembrane protein 63A).
SGD Description
Calcium permeable gated cation channel; functions as an osmosensitive, calcium-permeable cation channel when expressed in a heterologous system; may be involved in detoxification; similar to Arabidopsis CSC1
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13018:SF128
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
R64-5-1
Viewer Help
620.6k620.8k621.0k621.2k621.4k621.6k621.8k622.0k622.2k622.4k622.6k622.8k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions