related to yeast Vacuolar Protein Sorting factor 35
Synonyms
CELE_F59G1.3
F59G1.3
Biotype
protein coding gene
Automated Description
Involved in positive regulation of protein localization to cell periphery; protein localization to postsynaptic membrane; and regulation of presynapse assembly. Located in cytosol; dendrite; and neuronal cell body. Is expressed in several structures, including body wall musculature; ciliated neurons; coelomocyte; intestine; and pharynx. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 17. Orthologous to human VPS35 (VPS35 retromer complex component).
WB Description
Involved in positive regulation of protein localization to cell periphery; protein localization to postsynaptic membrane; and regulation of presynapse assembly. Located in cytosol; dendrite; and neuronal cell body. Expressed in several structures, including body wall musculature; ciliated neurons; coelomocyte; intestine; and pharynx. Human ortholog(s) of this gene implicated in Parkinson's disease 17. Is an ortholog of human VPS35 (VPS35 retromer complex component).