Gene

pitr-1

Species
Caenorhabditis elegans
Symbol
pitr-1
Name
PIT (mammalian phosphate transporter) Related 1
Synonyms
  • C48A7.2
  • CELE_C48A7.2
Biotype
protein coding gene
Automated Description
Predicted to enable phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Is expressed in several structures, including body wall musculature; germ line; hermaphrodite gonad; intestine; and nerve ring. Human ortholog(s) of this gene implicated in basal ganglia calcification. Orthologous to human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2).
WB Description
Predicted to enable phosphate transmembrane transporter activity. Predicted to be involved in phosphate ion transmembrane transport. Predicted to be located in membrane. Expressed in several structures, including body wall musculature; hermaphrodite gonad; intestine; nerve ring; and pharynx. Human ortholog(s) of this gene implicated in basal ganglia calcification. Is an ortholog of human SLC20A1 (solute carrier family 20 member 1) and SLC20A2 (solute carrier family 20 member 2).
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11101
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensSLC20A16 of 9YesNo   
Homo sapiensSLC20A26 of 9YesNo   
Mus musculusSlc20a17 of 9YesNo   
Mus musculusSlc20a27 of 9YesNo   
Rattus norvegicusSlc20a26 of 9YesNo   
Rattus norvegicusSlc20a16 of 9YesNo   
Xenopus tropicalisslc20a27 of 9YesNo   
Xenopus tropicalisslc20a17 of 9YesNo   
Danio rerioslc20a26 of 9YesNo   
Danio rerioslc20a1a6 of 9YesNo   
Danio rerioslc20a1b6 of 9YesNo   
Drosophila melanogasterNaPi-III7 of 9YesNo   
Saccharomyces cerevisiaePHO898 of 9YesYes   
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
pitr-3151960447 of 8  
pitr-2250861447 of 8  
pitr-5351759437 of 8  
pitr-6451452337 of 8  
pitr-4555349316 of 8  

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
yolk synthesis variant
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Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Alleles and Variants

Genome location
Assembly version
WBcel235
Viewer Help
7.3945M7.3950M7.3955M7.3960M7.3965M7.3970M7.3975M
Variant Types and ConsequencesOnly variants associated to alleles are shown in the graphics above. See all variants in JBrowse.
Allele/Variant Symbol
Allele Synonyms
Category
Variant
Variant type
Molecular consequence
Has Disease Annotations
Has Phenotype Annotations
tm3747allele
b1028allele
Yes
NC_003282.8:g.7394830T>Cvariant
SNP
  • missense variant
NC_003282.8:g.7395454A>Tvariant
SNP
  • intron variant
NC_003282.8:g.7394550A>Tvariant
SNP
  • intron variant
NC_003282.8:g.7395334C>Tvariant
SNP
  • missense variant
NC_003282.8:g.7396025C>Tvariant
SNP
  • synonymous variant
NC_003282.8:g.7394455A>Tvariant
SNP
  • intron variant
NC_003282.8:g.7394109C>Tvariant
SNP
  • missense variant
NC_003282.8:g.7397284A>Tvariant
SNP
  • 3 prime UTR variant
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Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location
Assembly version
WBcel235
Viewer Help
7.3945M7.3950M7.3955M7.3960M7.3965M7.3970M7.3975MC48A7.2a.1 (pitr-1)C48A7.2b.1 (pitr-1)T12B3.7T12B3.5 (21ur-12255)C48A7.9

Sequence Details

Transcript: Mode:
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Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

2 interactor genes based on 2 annotations
pitr-1 molecule type
Interactor gene
Interactor species
Interactor molecule type
Detection methods
Source
Reference
protein
ubq-1Caenorhabditis elegans
protein
  • affinity chromatography technology
PMID:34321666
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Genetic Interactions

pitr-1 role
pitr-1 genetic perturbation
Interactor gene
Interactor species
Interactor role
Interactor genetic perturbation
Interaction type
Phenotype or trait
Source
Reference
suppressor gene
let-7Caenorhabditis elegans
suppressed gene
n2853
genetic suppression
    PMID:16458514
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