Gene

pdha1

Species
Xenopus tropicalis
Symbol
pdha1
Name
pyruvate dehydrogenase E1 alpha 1 subunit
Synonyms
  • pdha
  • pdha1
Biotype
gene
Automated Description
Predicted to enable pyruvate dehydrogenase (acetyl-transferring) activity. Predicted to be involved in acetyl-CoA biosynthetic process from pyruvate. Predicted to act upstream of or within glucose metabolic process and pyruvate metabolic process. Predicted to be located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency and spermatogenic failure 70. Orthologous to human PDHA1 (pyruvate dehydrogenase E1 subunit alpha 1) and PDHA2 (pyruvate dehydrogenase E1 subunit alpha 2).
XBXT Description
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
XT9.1
Viewer Help
38.916M38.918M38.920M38.922M38.924M38.926M

Sequence Details

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Expression

Primary Sources
Other Sources
None
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions