Version: 8.0.0
Date: Tue Jan 28 2025
atp6v0ca
Danio rerioZFIN:ZDB-GENE-020419-23
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

atp6v0ca

Species
Danio rerio
Symbol
atp6v0ca
Name
ATPase H+ transporting V0 subunit ca
Synonyms
  • atp6l
  • atp6v0c
Biotype
protein coding gene
Automated Description
Predicted to enable proton-transporting ATPase activity, rotational mechanism. Acts upstream of or within several processes, including apical protein localization; embryonic retina morphogenesis in camera-type eye; and notochord cell vacuolation. Predicted to be located in clathrin-coated vesicle membrane; synaptic vesicle membrane; and vacuolar membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Predicted to be active in membrane. Is expressed in several structures, including digestive system; gonad; integument; nervous system; and unfertilized egg. Human ortholog(s) of this gene implicated in early-onset epilepsy 3 and thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10263
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
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    Based On
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCz11
            Viewer Help
            16.045M16.046M16.047M16.048M16.049M16.050M16.051M16.052M16.053M16.054M16.055M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            atp6v0ca molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
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              Genetic Interactions

              atp6v0ca role
              atp6v0ca genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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