Gene

dtl

Species
Danio rerio
Symbol
dtl
Name
denticleless E3 ubiquitin protein ligase homolog (Drosophila)
Synonyms
  • cb151
  • chunp6871
Biotype
protein coding gene
Automated Description
Predicted to enable protein-macromolecule adaptor activity. Predicted to contribute to ubiquitin-protein transferase activity. Involved in mitotic G2 DNA damage checkpoint signaling. Predicted to be located in centrosome. Predicted to be part of Cul4A-RING E3 ubiquitin ligase complex and Cul4B-RING E3 ubiquitin ligase complex. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; head; immature eye; mesoderm; and optic primordium. Orthologous to human DTL (denticleless E3 ubiquitin protein ligase homolog).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR22852
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
13.145M13.150M13.155M13.160M13.165M13.170M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions