Gene

igfbp1a

Species
Danio rerio
Symbol
igfbp1a
Name
insulin-like growth factor binding protein 1a
Synonyms
  • cb656
  • igfbp1
Biotype
protein coding gene
Automated Description
Enables insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Acts upstream of or within negative regulation of cell population proliferation; regeneration; and response to hypoxia. Located in cytoplasm. Is expressed in several structures, including adaxial cell; brain; cardiovascular system; digestive system; and gonad. Human ortholog(s) of this gene implicated in diabetic angiopathy. Orthologous to human IGFBP1 (insulin like growth factor binding protein 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11551
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
6.8090M6.8095M6.8100M6.8105M6.8110M6.8115M6.8120M6.8125M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions