Gene

slc1a2b

Species
Danio rerio
Symbol
slc1a2b
Name
solute carrier family 1 member 2b
Synonyms
  • eaat2
  • EAAT2a
Biotype
protein coding gene
Automated Description
Predicted to enable L-glutamate transmembrane transporter activity; glutamate:sodium symporter activity; and neutral L-amino acid transmembrane transporter activity. Acts upstream of or within larval locomotory behavior and regulation of glutamate uptake involved in transmission of nerve impulse. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in nervous system and spinal cord neural tube. Used to study developmental and epileptic encephalopathy 41. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 41. Orthologous to human SLC1A2 (solute carrier family 1 member 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11958
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCz11
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            37.398M37.399M37.400M37.401M37.402M37.403M37.404M37.405M37.406M37.407M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            slc1a2b molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
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              Genetic Interactions

              slc1a2b role
              slc1a2b genetic perturbation
              Interactor gene
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              Interactor role
              Interactor genetic perturbation
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