Gene

gnb1a

Species
Danio rerio
Symbol
gnb1a
Name
guanine nucleotide binding protein (G protein), beta polypeptide 1a
Synonyms
  • gnb1
  • wu:fb50b09
Biotype
protein coding gene
Automated Description
Predicted to enable signaling receptor complex adaptor activity. Acts upstream of or within positive regulation of neutrophil migration and posterior lateral line neuromast primordium migration. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Is expressed in several structures, including blastomere; brain; epidermis; fin; and sensory system. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia; autosomal dominant intellectual developmental disorder 42; congestive heart failure; and myelodysplastic syndrome. Orthologous to human GNB1 (G protein subunit beta 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19850

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

No data available

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions