Gene

tbxas1

Species
Danio rerio
Symbol
tbxas1
Name
thromboxane A synthase 1 (platelet)
Synonyms
  • wu:fk19d08
  • zgc:136708
Biotype
protein coding gene
Automated Description
Predicted to enable thromboxane-A synthase activity. Predicted to be located in membrane. Is expressed in heart. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome and cerebral infarction. Orthologous to human TBXAS1 (thromboxane A synthase 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24301
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
cyp3a65153156375 of 8  
cyp3c4253356355 of 8  
cyp3c3353156355 of 8  
cyp3c1453254315 of 8  

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
cardiac muscle cell shape, abnormal
myocardium bent, abnormal
pericardium edematous, abnormal
post-vent region increased curvature, abnormal
Showing 1 - 4 of 4 rows
per page

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume

Transgenic Alleles

No data available

Models

Model name
Experimental condition
Associated Human Diseases
Associated Phenotypes
Modifier
Source
AB + MO1-tbxas1
has condition:
standard conditions
  • cardiac muscle cell shape, abnormal
  • myocardium bent, abnormal
ZFIN
TL + MO2-tbxas1
has condition:
chemical treatment by environment 2,3,7,8-tetrachlorodibenzodioxine
  • pericardial cavity edematous, ameliorated
ZFIN
Showing 1 - 2 of 2 rows
per page

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
12.66M12.68M12.70M12.72M12.74M12.76M12.78M12.80M12.82M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Must provide at least one subject
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions