Gene

rad21a

Species
Danio rerio
Symbol
rad21a
Name
RAD21 cohesin complex component a
Synonyms
  • rad21
  • wu:fb55d02
Biotype
protein coding gene
Automated Description
Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including chordate embryonic development; enteric nervous system development; and heart development. Predicted to be located in several cellular components, including chromosome, centromeric region; nuclear matrix; and spindle pole. Predicted to be part of cohesin complex. Is expressed in several structures, including brain; digestive system; head; optic cup; and ventricular zone. Used to study Cornelia de Lange syndrome; brain cancer; and congenital heart disease. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; endometrial cancer; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human RAD21 (RAD21 cohesin complex component).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12585
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
48.410M48.412M48.414M48.416M48.418M48.420M48.422M48.424M48.426M48.428M48.430M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions