Version: 8.0.0Date: Tue Jan 28 2025
Gene
nrp1a
- Species
- Danio rerio
- Symbol
- nrp1a
- Name
- neuropilin 1a
- Synonyms
- np-1
- npn-1A
- Biotype
- protein coding gene
- Automated Description
- Enables vascular endothelial growth factor receptor activity. Involved in several processes, including positive regulation of cell migration involved in sprouting angiogenesis; positive regulation of filopodium assembly; and vascular endothelial growth factor receptor signaling pathway. Acts upstream of or within with a positive effect on angiogenesis involved in wound healing and cell activation. Acts upstream of or within several processes, including axon development; circulatory system development; and regulation of neuron projection development. Predicted to be located in membrane. Predicted to be active in axon; focal adhesion; and plasma membrane. Is expressed in several structures, including cardiovascular system; cranial neural crest cell; hematopoietic stem cell; hypochord; and nervous system. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and tetralogy of Fallot. Orthologous to human NRP1 (neuropilin 1).
- ZFIN Description
- Not Available
- Cross References
- Additional Information
- Literature
Orthology
- Gene tree
- PANTHER:PTHR44185
Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse
Phenotypes
- Primary Sources
- Other Sources
- None
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
No data available
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
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Sequence Feature Viewer
- Genome location
- Chr24:1162325...1304006 (141.68 kb)
- Assembly version
- GRCz11
- Viewer Help
Data currently unavailable; sequence viewer under construction
Expression
- Primary Sources
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.