Gene

irf6

Species
Danio rerio
Symbol
irf6
Name
interferon regulatory factor 6
Synonyms
  • zgc:63500
Biotype
protein coding gene
Automated Description
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in epidermis development. Acts upstream of or within embryonic neurocranium morphogenesis; epithelium development; and hard palate morphogenesis. Predicted to be active in nucleus. Is expressed in several structures, including blastoderm; digestive system; ethmoid cartilage; oral region; and sensory system. Human ortholog(s) of this gene implicated in several diseases, including Van der Woude syndrome; cleft lip; cleft palate; orofacial cleft 6; and popliteal pterygium syndrome. Orthologous to human IRF6 (interferon regulatory factor 6).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11949
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
1.172M1.174M1.176M1.178M1.180M1.182M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions