protein tyrosine phosphatase non-receptor type 11b
Synonyms
SHP3
zgc:63553
Biotype
protein coding gene
Automated Description
Enables phosphatase activity. Acts upstream of or within embryonic viscerocranium morphogenesis. Predicted to be active in cytoplasm. Is expressed in head. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome (multiple); Noonan syndrome with multiple lentigines 1; atrophic gastritis; juvenile myelomonocytic leukemia; and metachondromatosis. Orthologous to human PTPN11 (protein tyrosine phosphatase non-receptor type 11).