Gene

krt18b

Species
Danio rerio
Symbol
krt18b
Name
keratin 18b
Synonyms
  • keratin 18
  • krtt1c6
Biotype
protein coding gene
Automated Description
Predicted to enable structural molecule activity. Predicted to be involved in intermediate filament cytoskeleton organization. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Is expressed in several structures, including floor plate; sensory system; vein; yolk; and yolk syncytial layer. Human ortholog(s) of this gene implicated in liver cirrhosis and metabolic dysfunction-associated steatohepatitis. Orthologous to human KRT18 (keratin 18).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23239
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
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          Models

          Model name
          Experimental condition
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          Associated Phenotypes
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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCz11
            Viewer Help
            39.3605M39.3610M39.3615M39.3620M39.3625M39.3630M39.3635M39.3640M39.3645M39.3650M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            krt18b molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
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              Genetic Interactions

              krt18b role
              krt18b genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
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