Gene

abcc2

Species
Danio rerio
Symbol
abcc2
Name
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Synonyms
  • mrp2
  • zgc:66072
Biotype
protein coding gene
Automated Description
Predicted to enable ATPase-coupled transmembrane transporter activity. Acts upstream of or within cell redox homeostasis. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Human ortholog(s) of this gene implicated in bile duct disease (multiple); bilirubin metabolic disorder (multiple); leukemia (multiple); liver disease (multiple); and lung non-small cell carcinoma. Orthologous to human ABCC2 (ATP binding cassette subfamily C member 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24223
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
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685k690k695k700k705k710k

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions