Gene

grhprb

Species
Danio rerio
Symbol
grhprb
Name
glyoxylate reductase/hydroxypyruvate reductase b
Synonyms
  • fb80f04
  • wu:fb80f04
Biotype
protein coding gene
Automated Description
Predicted to enable glyoxylate reductase (NADPH) activity and hydroxypyruvate reductase (NADH) activity. Predicted to be active in cytosol. Is expressed in hypural; liver; pronephric duct; pronephros; and yolk syncytial layer. Human ortholog(s) of this gene implicated in primary hyperoxaluria and primary hyperoxaluria type 2. Orthologous to human GRHPR (glyoxylate and hydroxypyruvate reductase).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10996
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
19.836M19.837M19.838M19.839M19.840M19.841M19.842M19.843M19.844M19.845M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions