Version: 8.1.0
Date: Fri Apr 18 2025
uhrf1
Danio rerioZFIN:ZDB-GENE-040426-2039
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

uhrf1

Species
Danio rerio
Symbol
uhrf1
Name
ubiquitin-like with PHD and ring finger domains 1
Synonyms
  • fb97f09
  • NP95
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including hemi-methylated DNA-binding activity; methylated histone binding activity; and zinc ion binding activity. Acts upstream of or within several processes, including intestinal epithelial structure maintenance; lens development in camera-type eye; and negative regulation of gene expression via chromosomal CpG island methylation. Is active in cytoplasm and nucleus. Is expressed in several structures, including brain; eye; liver; pleuroperitoneal region; and presumptive neural retina. Orthologous to human UHRF1 (ubiquitin like with PHD and ring finger domains 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14140
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Must provide at least one subject
    Cell color indicative of annotation volume

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
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      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          GRCz11
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Must provide at least one subject
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          uhrf1 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection method
          Source
          Reference
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            Genetic Interactions

            uhrf1 role
            uhrf1 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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