Version: 8.0.0
Date: Tue Jan 28 2025
edem1
Danio rerioZFIN:ZDB-GENE-040426-808
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

edem1

Species
Danio rerio
Symbol
edem1
Name
ER degradation enhancer, mannosidase alpha-like 1
Synonyms
  • zgc:55816
Biotype
protein coding gene
Automated Description
Predicted to enable calcium ion binding activity and mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to act upstream of or within carbohydrate metabolic process; endoplasmic reticulum mannose trimming; and mannose trimming involved in glycoprotein ERAD pathway. Predicted to be located in endoplasmic reticulum and membrane. Is expressed in anterior axial hypoblast; hatching gland; head; liver; and polster. Orthologous to human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11742
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    No data available

    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
      Expressed components
      Knock-down targets
      Regulatory regions
      Has Disease Annotations
      Has Phenotype Annotations
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        Models

        Model name
        Experimental condition
        Associated Human Diseases
        Associated Phenotypes
        Modifier
        Source
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          Sequence Feature Viewer

          Genome location
          Assembly version
          GRCz11
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          Data currently unavailable; sequence viewer under construction

          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          edem1 molecule type
          Interactor gene
          Interactor species
          Interactor molecule type
          Detection methods
          Source
          Reference
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            Genetic Interactions

            edem1 role
            edem1 genetic perturbation
            Interactor gene
            Interactor species
            Interactor role
            Interactor genetic perturbation
            Interaction type
            Phenotype or trait
            Source
            Reference
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