Version: 8.0.0
Date: Tue Jan 28 2025
ppm1da
Danio rerioZFIN:ZDB-GENE-040426-815
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

ppm1da

Species
Danio rerio
Symbol
ppm1da
Name
protein phosphatase, Mg2+/Mn2+ dependent, 1Da
Synonyms
  • ppm1d
  • wu:fj44c08
Biotype
protein coding gene
Automated Description
Predicted to enable mitogen-activated protein kinase binding activity and protein serine/threonine phosphatase activity. Predicted to be involved in negative regulation of gene expression, epigenetic and regulation of intracellular signal transduction. Predicted to act upstream of or within protein dephosphorylation. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human PPM1D (protein phosphatase, Mg2+/Mn2+ dependent 1D).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR13832
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensPPM1D8 of 10YesNo☑ ☑☐☑☑☑☑☑☐ ☑
Mus musculusPpm1d10 of 10YesYes☑ ☑☑☑☑☑☑☑☑ ☑
Rattus norvegicusPpm1d9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Xenopus tropicalisppm1d9 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Drosophila melanogasterPp2C14 of 10YesYes☑ ☐☐☐☐☑☑☑☐ ☐
Caenorhabditis elegansppm-1.D6 of 9YesYes☑ ☐☐☐☑☑☑☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
ppm1db155767547 of 8☑ ☑☐☑☑☑☑☑ 
ppm1bb250237243 of 8☑ ☐☐☐☐☑☑☐ 
ppm1ba344138243 of 8☑ ☐☐☐☐☑☑☐ 
pdp2449735222 of 8☑ ☐☐☐☐☐☑☐ 
ppm1nb536042303 of 8☑ ☐☐☐☐☑☑☐ 
ppm1e639741282 of 8☑ ☐☐☐☐☐☑☐ 
ppm1na738142253 of 8☑ ☐☐☐☐☑☑☐ 
ppm1kb836243243 of 8☑ ☐☐☐☐☑☑☐ 
ppm1h944037222 of 8☑ ☐☐☐☐☐☑☐ 
ilkap1039039262 of 8☑ ☐☐☐☐☐☑☐ 
ppm1la1138140272 of 8☑ ☐☐☐☐☐☑☐ 
ppm1ab1233043283 of 8☑ ☐☐☐☐☑☑☐ 
ppm1f1337639272 of 8☑ ☐☐☐☐☐☑☐ 
si:ch211-15p9.21442633222 of 8☑ ☐☐☐☐☐☑☐ 
ppm1aa1528444303 of 8☑ ☐☐☐☐☑☑☐ 
ppm1j1640235202 of 8☑ ☐☐☐☐☐☑☐ 
ppm1ka1729144263 of 8☑ ☐☐☐☐☑☑☐ 
ppm1g1832641242 of 8☑ ☐☐☐☐☐☑☐ 
pdp11935634232 of 8☑ ☐☐☐☐☐☑☐ 
ppm1lb2028142282 of 8☑ ☐☐☐☐☐☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    Genome location
    Assembly version
    GRCz11
    Viewer Help
    Data currently unavailable; sequence viewer under construction
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    la027625Tg
    • la027625
    		allele
    la012707Tg
    • la012707
    		allele
    la012708Tg
    • la012708
    		allele
    ihb226allele with one associated variant
    deletion
    • frameshift variant
    sa22658allele with one associated variant
    point mutation
    • stop gained
    ihb227allele with one associated variant
    insertion
    • frameshift variant
    sa42560allele with one associated variant
    point mutation
    • stop gained
    Showing 1 - 7 of 7 rows
    per page
    View detailed Alleles/Variants information
    Download all Alleles/Variants for all genes of the species

    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    GRCz11
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

    Transcript: Mode:

    Expression

    Primary Sources
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available