Gene

e2f8

Species
Danio rerio
Symbol
e2f8
Name
E2F transcription factor 8
Synonyms
  • im:7149356
  • si:ch211-215h6.2
Biotype
protein coding gene
Automated Description
Enables DNA binding activity and DNA-binding transcription factor activity. Involved in positive regulation of transcription by RNA polymerase II and sprouting angiogenesis. Acts upstream of or within lymphangiogenesis; motor neuron axon guidance; and negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including axis; caudal vein plexus; eye; liver; and proliferative region. Orthologous to human E2F8 (E2F transcription factor 8).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12081
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
16.578M16.580M16.582M16.584M16.586M16.588M16.590M16.592M16.594M16.596M16.598M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions