Version: 8.0.0
Date: Tue Jan 28 2025
klhl12
Danio rerioZFIN:ZDB-GENE-041114-205
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

klhl12

Species
Danio rerio
Symbol
klhl12
Name
kelch-like family member 12
Synonyms
  • wu:fi60g03
  • zgc:92570
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Acts upstream of or within Wnt signaling pathway; anterior/posterior pattern specification; and convergent extension involved in axis elongation. Predicted to be located in cytoplasmic vesicle. Predicted to be part of COPII vesicle coat and Cul3-RING ubiquitin ligase complex. Predicted to be active in COPII-coated ER to Golgi transport vesicle. Orthologous to human KLHL12 (kelch like family member 12).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24412
No data available

Paralogy

Function - GO Annotations

No function available for that gene

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Download all Alleles/Variants for all genes of the species

        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            No data available

            Sequence Details

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            Expression

            Primary Sources
            None
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            klhl12 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              klhl12 role
              klhl12 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
              Reference
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