Version: 8.0.0Date: Tue Jan 28 2025
Gene
apoa1b
- Species
- Danio rerio
- Symbol
- apoa1b
- Name
- apolipoprotein A-Ib
- Synonyms
- wu:fb66d03
- wu:fd19c08
- Biotype
- protein coding gene
- Automated Description
- Predicted to enable cholesterol transfer activity; phosphatidylcholine-sterol O-acyltransferase activator activity; and phospholipid binding activity. Predicted to be involved in several processes, including acylglycerol homeostasis; cholesterol efflux; and phospholipid efflux. Predicted to act upstream of or within lipid transport; lipoprotein metabolic process; and steroid metabolic process. Predicted to be located in extracellular region. Predicted to be part of several cellular components, including chylomicron; low-density lipoprotein particle; and very-low-density lipoprotein particle. Predicted to be active in extracellular vesicle. Is expressed in blood; liver; otolith; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); familial hypercholesterolemia; hypolipoproteinemia (multiple); metabolic dysfunction-associated steatohepatitis; and systemic lupus erythematosus. Orthologous to human APOA1 (apolipoprotein A1).
- ZFIN Description
- Not Available
- Cross References
- Additional Information
- Literature
Phenotypes
- Primary Sources
- None
- Other Sources
- None
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Disease Associations
Cases where the expected disease association was NOT found
Cell color indicative of annotation volume
No data available
Alleles and Variants
Allele/Variant Symbol | Allele Synonyms | Category | Variant | Variant type | Molecular consequence | Has Disease Annotations | Has Phenotype Annotations |
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Transgenic Alleles
Species (carrying the transgene) | Allele symbol | Transgenic construct | Expressed components | Knock-down targets | Regulatory regions | Has Disease Annotations | Has Phenotype Annotations |
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Models
Model name | Experimental condition | Associated Human Diseases | Associated Phenotypes | Modifier | Source |
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Expression
- Primary Sources
- Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.