Enables nuclear receptor activity. Acts upstream of or within several processes, including embryonic viscerocranium morphogenesis; regulation of intestinal lipid absorption; and regulation of transcription by RNA polymerase II. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; digestive system; eye; heart; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in cerebral infarction; cerebrovascular disease; myocardial infarction; and obesity. Orthologous to human NR1H3 (nuclear receptor subfamily 1 group H member 3).