Gene

abcb11a

Species
Danio rerio
Symbol
abcb11a
Name
ATP-binding cassette, sub-family B (MDR/TAP), member 11a
Synonyms
  • fc21d02
  • wu:fc21d02
Biotype
protein coding gene
Automated Description
Predicted to enable ABC-type bile acid transporter activity and canalicular bile acid transmembrane transporter activity. Predicted to be involved in canalicular bile acid transport and transmembrane transport. Predicted to be located in membrane. Predicted to be active in apical plasma membrane. Is expressed in intestine. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 2; intrahepatic cholestasis; liver cirrhosis; and progressive familial intrahepatic cholestasis 2. Orthologous to human ABCB11 (ATP binding cassette subfamily B member 11).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24221
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
48.765M48.770M48.775M48.780M48.785M48.790M48.795M48.800M48.805M48.810M48.815M

Sequence Details

Loading...

Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions