Gene

celsr1b

Species
Danio rerio
Symbol
celsr1b
Name
cadherin EGF LAG seven-pass G-type receptor 1b
Synonyms
  • celsr5
  • flamingo 1b
Biotype
protein coding gene
Automated Description
Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Acts upstream of or within cell migration involved in gastrulation; heart development; and neural tube development. Predicted to be located in plasma membrane. Is expressed in several structures, including central nervous system; eye; notochord; pleuroperitoneal region; and spinal cord neural tube. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CELSR1 (cadherin EGF LAG seven-pass G-type receptor 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24026
No data available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
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      Alleles and Variants

      Allele/Variant Symbol
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      Variant
      Variant type
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
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          Models

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            Sequence Feature Viewer

            Genome location
            Assembly version
            GRCz11
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            19.76M19.77M19.78M19.79M19.80M19.81M19.82M19.83M19.84M19.85M19.86M

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            celsr1b molecule type
            Interactor gene
            Interactor species
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              Genetic Interactions

              celsr1b role
              celsr1b genetic perturbation
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