Gene

itga2b

Species
Danio rerio
Symbol
itga2b
Name
integrin, alpha 2b
Synonyms
  • CD41
  • GPIIb
Biotype
protein coding gene
Automated Description
Predicted to enable integrin binding activity. Acts upstream of or within angiogenesis; blood coagulation; and endothelial cell proliferation. Part of integrin complex. Is expressed in blood; thrombocyte; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in Glanzmann's thrombasthenia; platelet-type bleeding disorder 16; thrombocytopenia; and von Willebrand's disease 1. Orthologous to human ITGA2B (integrin subunit alpha 2b).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR23220
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
21.355M21.360M21.365M21.370M21.375M21.380M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions