Gene

hps1

Species
Danio rerio
Symbol
hps1
Name
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1
Synonyms
  • im:7143944
  • zgc:123240
Biotype
protein coding gene
Automated Description
Predicted to contribute to guanyl-nucleotide exchange factor activity. Predicted to be involved in melanosome assembly. Predicted to act upstream of or within vesicle-mediated transport. Predicted to be part of BLOC-3 complex. Is expressed in optic vesicle; pancreas; pancreatic bud; retina; and retinal pigmented epithelium. Used to study proteinuria. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 1 and oculocutaneous albinism. Orthologous to human HPS1 (HPS1 biogenesis of lysosomal organelles complex 3 subunit 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12761
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
40.690M40.695M40.700M40.705M40.710M40.715M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions