Gene

phf8

Species
Danio rerio
Symbol
phf8
Name
PHD finger protein 8
Synonyms
None
Biotype
protein coding gene
Automated Description
Predicted to enable several functions, including histone demethylase activity; methylated histone binding activity; and transcription coregulator activity. Involved in brain development and positive regulation of DNA-templated transcription. Acts upstream of or within embryonic organ development; posterior lateral line neuromast deposition; and regulation of neuron apoptotic process. Predicted to be located in nucleolus. Is expressed in head; otic vesicle; posterior lateral line system; and tail bud. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Siderius type. Orthologous to human PHF8 (PHD finger protein 8).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
27.594M27.596M27.598M27.600M27.602M27.604M27.606M27.608M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions