Gene

ptpn22

Species
Danio rerio
Symbol
ptpn22
Name
protein tyrosine phosphatase non-receptor type 22
Synonyms
  • si:dkey-78k11.1
Biotype
protein coding gene
Automated Description
Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within heart development. Predicted to be active in cytoplasm and nucleus. Is expressed in heart and heart tube. Human ortholog(s) of this gene implicated in several diseases, including Addison's disease; Meniere's disease; autoimmune disease (multiple); graft-versus-host disease; and pulmonary tuberculosis. Orthologous to several human genes including PTPN22 (protein tyrosine phosphatase non-receptor type 22).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR19134
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
26.144M26.146M26.148M26.150M26.152M26.154M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions