Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in brain; head mesenchyme; post-vent vasculature; trunk vasculature; and yolk syncytial layer. Orthologous to several human genes including PJA2 (praja ring finger ubiquitin ligase 2).