Gene

scn1lab

Species
Danio rerio
Symbol
scn1lab
Name
sodium channel, voltage-gated, type I like, alpha b
Synonyms
  • did
  • didy
Biotype
protein coding gene
Automated Description
Predicted to enable voltage-gated sodium channel activity. Acts upstream of or within several processes, including neuronal action potential; regulation of generation of precursor metabolites and energy; and swimming behavior. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated sodium channel complex. Predicted to be active in axon. Is expressed in heart and nervous system. Used to study Dravet syndrome; anxiety disorder; and epilepsy. Human ortholog(s) of this gene implicated in epilepsy (multiple); episodic ataxia type 9; erythromelalgia; familial hemiplegic migraine 3; and paroxysmal extreme pain disorder. Orthologous to several human genes including SCN3A (sodium voltage-gated channel alpha subunit 3).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR10037
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
10.25M10.26M10.27M10.28M10.29M10.30M10.31M10.32M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions