Gene

fas

Species
Danio rerio
Symbol
fas
Name
Fas cell surface death receptor
Synonyms
None
Biotype
protein coding gene
Automated Description
Predicted to enable tumor necrosis factor receptor activity. Acts upstream of or within notochord development and positive regulation of apoptotic process. Predicted to be located in membrane. Predicted to be part of CD95 death-inducing signaling complex. Predicted to be active in external side of plasma membrane and membrane raft. Is expressed in several structures, including blastoderm; digestive system; eye; notochord; and ovary. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); cystic fibrosis; hematologic cancer (multiple); pre-eclampsia (multiple); and urinary system cancer (multiple). Orthologous to human FAS (Fas cell surface death receptor).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
23.620M23.622M23.624M23.626M23.628M23.630M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions