Gene

sgms2a

Species
Danio rerio
Symbol
sgms2a
Name
sphingomyelin synthase 2a
Synonyms
  • sgms2
Biotype
protein coding gene
Automated Description
Predicted to enable ceramide cholinephosphotransferase activity and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process and sphingomyelin biosynthetic process. Predicted to act upstream of or within sphingolipid metabolic process. Predicted to be located in membrane. Predicted to be active in Golgi membrane; endoplasmic reticulum membrane; and plasma membrane. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Orthologous to human SGMS2 (sphingomyelin synthase 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR21290
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
49.934M49.936M49.938M49.940M49.942M49.944M49.946M49.948M49.950M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions