Gene

irak1

Species
Danio rerio
Symbol
irak1
Name
interleukin-1 receptor-associated kinase 1
Synonyms
None
Biotype
protein coding gene
Automated Description
Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in cell surface receptor signaling pathway; intracellular signal transduction; and positive regulation of canonical NF-kappaB signal transduction. Predicted to act upstream of or within protein phosphorylation and signal transduction. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in ankylosing spondylitis; diffuse scleroderma; psoriatic arthritis; and squamous cell carcinoma. Orthologous to human IRAK1 (interleukin 1 receptor associated kinase 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR24419
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
7.575M7.580M7.585M7.590M7.595M7.600M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions