Version: 8.0.0
Date: Tue Jan 28 2025
irf3
Danio rerioZFIN:ZDB-GENE-071120-7
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

irf3

Species
Danio rerio
Symbol
irf3
Name
interferon regulatory factor 3
Synonyms
None
Biotype
protein coding gene
Automated Description
Enables transcription cis-regulatory region binding activity. Predicted to be involved in immune system process and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in head kidney. Human ortholog(s) of this gene implicated in brain disease. Orthologous to human IRF3 (interferon regulatory factor 3).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11949
Stringency:
Additional filters to further constrain the results:
Species Gene symbol Count Best Best reverse
Method
Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiensIRF38 of 10YesYes☑ ☑☐☑☑☑☑☑☐ ☑
Mus musculusIrf39 of 10YesYes☑ ☑☐☑☑☑☑☑☑ ☑
Rattus norvegicusIrf39 of 9YesYes☑ ☑☑☑☑☑☑☑☑  
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Gene symbolRank Alignment Length (aa) Similarity %Identity %Method Count
Method
Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
irf5151841253 of 8☑ ☐☐☐☐☑☑☐ 
irf7245945283 of 8☑ ☐☐☐☐☑☑☐ 
irf6349041263 of 8☑ ☐☐☐☐☑☑☐ 
irf9448241243 of 8☑ ☐☐☐☐☑☑☐ 
irf4a548740253 of 8☑ ☐☐☐☐☑☑☐ 
irf8646142253 of 8☑ ☐☐☐☐☑☑☐ 
irf4b745340253 of 8☑ ☐☐☐☐☑☑☐ 
irf10843040263 of 8☑ ☐☐☐☐☑☑☐ 
irf1b935635223 of 8☑ ☐☐☐☐☑☑☐ 
irf1a1025537283 of 8☑ ☐☐☐☐☑☑☐ 
irf2b1122840283 of 8☑ ☐☐☐☐☑☑☐ 
irf2a1222739273 of 8☑ ☐☐☐☐☑☑☐ 

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None
No data available

Disease Associations

Cases where the expected disease association was NOT found
Must provide at least one subject
Cell color indicative of annotation volume
Species
Gene
Association
Disease Qualifier
Disease
Evidence
Source
Based On
References
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    Alleles and Variants

    No mapped variant information available
    Allele/Variant Symbol
    Allele Synonyms
    Category
    Variant
    Variant type
    Molecular consequence
    Has Disease Annotations
    Has Phenotype Annotations
    ihbjsk1allele
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    View detailed Alleles/Variants information
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    Transgenic Alleles

    No data available

    Models

    No data available

    Sequence Feature Viewer

    Genome location
    Assembly version
    GRCz11
    Viewer Help
    Data currently unavailable; sequence viewer under construction

    Sequence Details

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    Expression

    Primary Sources
    Other Sources
    Must provide at least one subject
    Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

    Molecular Interactions

    No data available

    Genetic Interactions

    No data available