Gene

grik2

Species
Danio rerio
Symbol
grik2
Name
glutamate receptor, ionotropic, kainate 2
Synonyms
  • grik2alpha
  • grik2l
Biotype
protein coding gene
Automated Description
Predicted to enable glutamate-gated calcium ion channel activity and kainate selective glutamate receptor activity. Acts upstream of or within detection of cold stimulus involved in thermoception and response to cold. Predicted to be located in plasma membrane. Is expressed in several structures, including heart; integument; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Huntington's disease and autosomal recessive intellectual developmental disorder 6. Orthologous to human GRIK2 (glutamate ionotropic receptor kainate type subunit 2).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
Not Available

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
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    Disease Associations

    Cases where the expected disease association was NOT found
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    Alleles and Variants

    Allele/Variant Symbol
    Allele Synonyms
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    Variant type
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      Transgenic Alleles

      Species
      (carrying the transgene)
      Allele symbol
      Transgenic construct
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        Models

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          Sequence Feature Viewer

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          Sequence Details

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          Expression

          Primary Sources
          Other Sources
          Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

          Molecular Interactions

          grik2 molecule type
          Interactor gene
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            Genetic Interactions

            grik2 role
            grik2 genetic perturbation
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