Species

Danio rerio

Symbol

tpra

Name

translocated promoter region a, nuclear basket protein

Synonyms

si:ch1073-412d11.1

Biotype

protein coding gene

Automated Description

Predicted to be a structural constituent of nuclear pore. Predicted to be involved in mRNA export from nucleus and regulation of mitotic spindle assembly. Predicted to act upstream of or within protein import into nucleus. Predicted to be part of nuclear pore. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder. Orthologous to human TPR (translocated promoter region, nuclear basket protein).

ZFIN Description

Not Available

Cross References

Additional Information

Literature

Orthology

Gene tree: PANTHER:PTHR18898

Stringency:StringentModerateNo filter

Additional filters to further constrain the results:

Best Score OnlyBest Reverse Score Only

Count:Species:Methods:

Species	Gene symbol	Count	Best	Best reverse	Method Ensembl ComparaHGNCHieranoidInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidXenbaseZFIN
Homo sapiens	TPR	6 of 10	Yes	No	☐ ☑☐☑☑☑☑☐☐ ☑
Mus musculus	Tpr	6 of 10	Yes	No	☐ ☑☐☑☑☑☑☐☐ ☑
Rattus norvegicus	Tpr	5 of 9	Yes	No	☐ ☑☐☑☑☑☑☐☐
Xenopus tropicalis	tpr	3 of 9	Yes	No	☐ ☐☐☑☑☐☑☐☐
Drosophila melanogaster	Mgtor	8 of 10	Yes	Yes	☑ ☑☑☑☑☑☑☑☐ ☐
Caenorhabditis elegans	npp-21	4 of 9	Yes	Yes	☐ ☑☑☑☐☐☑☐☐
Saccharomyces cerevisiae	MLP2	5 of 9	Yes	Yes	☐ ☑☑☑☑☐☑☐☐
Saccharomyces cerevisiae	MLP1	5 of 9	Yes	No	☐ ☑☑☐☑☑☑☐☐

Links to orthology data in JBrowse by filter level: Stringent, Moderate, No filter, Best and Best Reverse

Paralogy

Gene symbol	Rank	Alignment Length (aa)	Similarity %	Identity %	Method Count	Method Ensembl ComparaHGNCInParanoidOMAOrthoFinderOrthoInspectorPANTHERPhylomeDBSonicParanoidSGD
tprb	1	2402	75	56	7 of 8	☑ ☑☐☑☑☑☑☑

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources: None
Other Sources: None

No data available

Disease Associations

Must provide at least one subject

Cell color indicative of annotation volume

Species	Gene	Association	Disease Qualifier	Disease	Evidence	Source	Based On	References
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Alleles and Variants

Genome location

Chr2:20811677...20866758 (55.08 kb)

Assembly version

GRCz11

Viewer Help

Data currently unavailable; sequence viewer under construction

Allele/Variant Symbol	Allele Synonyms	Category	Variant
sa44527		allele
la023496Tg	la023496	allele
sa32890		allele with one associated variant	NC_007113.7:g.20824364G>T point mutation stop gained
sa32892		allele with one associated variant	NC_007113.7:g.20863360G>A point mutation stop gained
sa19727		allele with one associated variant	NC_007113.7:g.20849256A>C point mutation stop gained
sa10563		allele with one associated variant	NC_007113.7:g.20864889A>C point mutation stop gained
sa32891		allele with one associated variant	NC_007113.7:g.20862881G>T point mutation stop gained
sa25104		allele with one associated variant	NC_007113.7:g.20849198C>T point mutation splice donor variant

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View detailed Alleles/Variants information

Download all Alleles/Variants for all genes of the species

Transgenic Alleles

No data available

Models

No data available

Sequence Feature Viewer

Genome location

Chr2:20811677...20866758 (55.08 kb)

Assembly version

GRCz11

Viewer Help

Data currently unavailable; sequence viewer under construction

Sequence Details

Transcript: Mode:

Expression

Primary Sources

None

Other Sources

Must provide at least one subject

Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

No data available

Genetic Interactions

No data available