Gene

huwe1

Species
Danio rerio
Symbol
huwe1
Name
HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1
Synonyms
  • sb:eu595
  • sb:eu633
Biotype
protein coding gene
Automated Description
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including Golgi organization; base-excision repair; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within DNA repair. Predicted to be active in Golgi membrane and nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Turner type. Orthologous to human HUWE1 (HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11254
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
28.50M28.51M28.52M28.53M28.54M28.55M28.56M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions