Enables arachidonate 5-lipoxygenase activity; arachidonate monooxygenase activity; and leukotriene-C4 synthase activity. Acts upstream of or within arachidonate metabolic process and inflammatory response to wounding. Predicted to be located in cytoplasm. Predicted to be active in nuclear envelope. Is expressed in pronephric duct. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma (multiple); pancreatic cancer; and pulmonary tuberculosis. Orthologous to human ALOX5 (arachidonate 5-lipoxygenase).