Gene

alox5a

Species
Danio rerio
Symbol
alox5a
Name
arachidonate 5-lipoxygenase a
Synonyms
  • ALOX2
  • alox5
Biotype
protein coding gene
Automated Description
Enables arachidonate 5-lipoxygenase activity; arachidonate monooxygenase activity; and leukotriene-C4 synthase activity. Acts upstream of or within arachidonate metabolic process and inflammatory response to wounding. Predicted to be located in cytoplasm. Predicted to be active in nuclear envelope. Is expressed in pronephric duct. Human ortholog(s) of this gene implicated in artery disease (multiple); asthma (multiple); pancreatic cancer; and pulmonary tuberculosis. Orthologous to human ALOX5 (arachidonate 5-lipoxygenase).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR11771
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
18.130M18.135M18.140M18.145M18.150M18.155M18.160M18.165M18.170M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions