Gene

ccdc88c

Species
Danio rerio
Symbol
ccdc88c
Name
coiled-coil domain containing 88C
Synonyms
  • zDAPLE
Biotype
protein coding gene
Automated Description
Enables guanyl-nucleotide exchange factor activity. Involved in neural tube formation and small GTPase-mediated signal transduction. Predicted to be located in cell junction. Predicted to be active in centrosome and cytoplasm. Is expressed in anterior neural tube; neural rod; and neural tube. Human ortholog(s) of this gene implicated in hydrocephalus and spinocerebellar ataxia type 40. Orthologous to human CCDC88C (coiled-coil domain containing 88C).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR18947
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
38.61M38.62M38.63M38.64M38.65M38.66M38.67M38.68M38.69M38.70M38.71M

Sequence Details

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Expression

Primary Sources
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions