Gene

rubcn

Species
Danio rerio
Symbol
rubcn
Name
rubicon autophagy regulator
Synonyms
  • si:ch1073-167a23.1
  • si:ch1073-280h16.1
Biotype
protein coding gene
Automated Description
Predicted to enable phosphatidylinositol phosphate binding activity. Predicted to be involved in negative regulation of autophagosome maturation and negative regulation of endocytosis. Predicted to act upstream of or within autophagy. Predicted to be located in endosome. Predicted to be active in early endosome and late endosome. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 15. Orthologous to human RUBCN (rubicon autophagy regulator).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR12326
Links to orthology data in JBrowse by filter level: Stringent,  Moderate,  No filter,  Best and Best Reverse

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
None
Other Sources
None

Disease Associations

Cases where the expected disease association was NOT found
Cell color indicative of annotation volume

Transgenic Alleles

Models

Sequence Feature Viewer

Genome location
Assembly version
GRCz11
Viewer Help
35.280M35.285M35.290M35.295M35.300M35.305M35.310M

Sequence Details

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Expression

Primary Sources
None
Other Sources
Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

Molecular Interactions

Genetic Interactions