Version: 8.0.0
Date: Tue Jan 28 2025
dhx58
Danio rerioZFIN:ZDB-GENE-120612-3
SummaryOrthologyParalogyFunction - GO AnnotationsPathwaysPhenotypesDisease AssociationsAlleles and VariantsTransgenic AllelesModelsSequence Feature ViewerSequence DetailsExpressionMolecular InteractionsGenetic Interactions
Gene

dhx58

Species
Danio rerio
Symbol
dhx58
Name
DEXH (Asp-Glu-X-His) box polypeptide 58
Synonyms
  • LGP2
Biotype
protein coding gene
Automated Description
Predicted to enable double-stranded RNA binding activity; single-stranded RNA binding activity; and zinc ion binding activity. Predicted to be involved in antiviral innate immune response; cytoplasmic pattern recognition receptor signaling pathway; and negative regulation of RIG-I signaling pathway. Predicted to act upstream of or within innate immune response. Predicted to be active in cytoplasm. Is expressed in gill; head kidney; liver; posterior kidney; and spleen. Orthologous to human DHX58 (DExH-box helicase 58).
ZFIN Description
Not Available
Cross References
Additional Information
Literature

Orthology

Gene tree
PANTHER:PTHR14074
No data available

Paralogy

Function - GO Annotations

Pathways

No data available

Phenotypes

Primary Sources
Other Sources
None
Phenotype Term
Annotation details
References
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    Disease Associations

    Cases where the expected disease association was NOT found
    Cell color indicative of annotation volume
    Gene
    Association
    Disease Qualifier
    Disease
    Evidence
    Source
    Based On
    References
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      Alleles and Variants

      Allele/Variant Symbol
      Allele Synonyms
      Category
      Variant
      Variant type
      Molecular consequence
      Has Disease Annotations
      Has Phenotype Annotations
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        Transgenic Alleles

        Species
        (carrying the transgene)
        Allele symbol
        Transgenic construct
        Expressed components
        Knock-down targets
        Regulatory regions
        Has Disease Annotations
        Has Phenotype Annotations
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          Models

          Model name
          Experimental condition
          Associated Human Diseases
          Associated Phenotypes
          Modifier
          Source
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            Sequence Feature Viewer

            No data available

            Sequence Details

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            Expression

            Primary Sources
            Other Sources
            Cell color indicative of annotation volume; red slash indicates species lacks structure or developmental stage.

            Molecular Interactions

            dhx58 molecule type
            Interactor gene
            Interactor species
            Interactor molecule type
            Detection methods
            Source
            Reference
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              Genetic Interactions

              dhx58 role
              dhx58 genetic perturbation
              Interactor gene
              Interactor species
              Interactor role
              Interactor genetic perturbation
              Interaction type
              Phenotype or trait
              Source
              Reference
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